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Endocrine Abstracts

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ea0003p269 | Steroids | BES2002

Size at birth, gestational age and cortisol secretion in adult life: Do multiple mechanisms underlie fetal programming of the hypothalamic-pituitary-adrenal axis?

Kajantie E , Phillips D , Dunkel L , Andersson S , Barker D , Forsen T , Osmond C , Wood P , Tuominen J , Eriksson J

Objective. Recent studies suggest that in utero programming of the hypothalamo-pituitary-adrenal axis is important in explaining the link between small size at birth and adult cardiovascular disease. We therefore examined the relationship between adult cortisol concentration and measurements at birth.Subjects. 420 men and women (mean age 69.5, range 65.0-75.8 yrs) born and living in Helsinki, Finland, with detailed birth records.<p class="ab...
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Published by BioScientifica

Endocrine Abstracts
ISSN 1470-3947 (print) | ISSN 1479-6848 (online)
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